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2 results for "Klotho beta" in Products
Klotho beta Products
Klotho beta is expressed primarily in the liver and pancreas and functions as a cofactor for FGF-19 subfamily member interactions with their receptors. It facilitates human FGF-19 (mouse FGF-15) binding to FGF R4 in the liver to inhibit bile acid synthesis. It also enhances FGF-21 binding to FGF R1c in adipocytes, leading to increased Insulin-dependent glucose uptake.
Recombinant Monoclonal Antibody
Reactivity:
Human
Details:
Human IgG1 Monoclonal Clone #RG7992
Applications:
ELISA, Flow, Func
Recombinant Monoclonal Antibody
Reactivity:
Human
Details:
Human IgG1 Monoclonal Clone #NGM313
Applications:
ELISA, Flow, Func