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3 results for "Klotho beta Proteins and Enzymes" in Products
Klotho beta Proteins and Enzymes
Klotho beta is expressed primarily in the liver and pancreas and functions as a cofactor for FGF-19 subfamily member interactions with their receptors. It facilitates human FGF-19 (mouse FGF-15) binding to FGF R4 in the liver to inhibit bile acid synthesis. It also enhances FGF-21 binding to FGF R1c in adipocytes, leading to increased Insulin-dependent glucose uptake.
Reactivity:
Mouse
Source:
NS0
Accession #:
NP_112457
Applications:
Bioactivity
Reactivity:
Human
Source:
NS0
Accession #:
Q86Z14
Applications:
Bioactivity
Reactivity:
Human
Source:
NS0
Accession #:
Q86Z14
Applications:
Bioactivity