3 results for "Integrin alpha 2/CD49b Small Molecules and Peptides" in Products
Integrin alpha 2/CD49b: Small Molecules and Peptides
Integrin alpha 2 is one of twelve Integrin alpha subunits that associates with the beta 1 subunit. Integrin alpha 2 beta 1 (VLA-2) is one of twelve integrin family adhesion receptors that share the beta 1 subunit. It is one of six very late antigens expressed on activated T cells. Divalent cations and intracellular (inside-out) signaling convert it to its most active, extended, and open conformation. a2b1 binds to Collagen types I, II, and III, Laminin, Decorin, E‑Cadherin, and Collectin ...
Selective inhibitor of integrin α2β1
| Chemical Name: | 1-(4-Fluorophenyl)-N-methyl-N-[4[[(phenylamino)carbonyl]amino]phenyl]-1H-pyrazole-4-sulfonamide |
| Purity: | ≥98% (HPLC) |
Potent α2β1 inhibitor; displays antithrombotic activity in vivo
| Chemical Name: | N-[[(4R)-5,5-Dimethyl-3-(phenylsulfonyl)-4-thiazolidinyl]carbonyl]-3-[[[(phenylmethyl)amino]carbonyl]amino]-L-alanine |
| Purity: | ≥98% (HPLC) |
α2 integrin inhibitor; anti-angiogenic
| Chemical Name: | 3-Cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzenesulfonamide |
| Purity: | ≥98% (HPLC) |
