303 results for "IL-28A/IFN-lambda 2" in Products
IL-28A/IFN-lambda 2 Products
IL‑28A/Interferon-lambda 2) is a type III interferon that is upregulated in response to viral infection. It acts primarily on epithelial cells through a receptor complex that contains IL-10 R beta and IL-28 R alpha/IFN-lambda R1. IL-28A promotes the Th1 polarization of dendritic cells in the airway (e.g. production of IL-12 p70 and IFN-gamma) and inhibits Th2 and Th17 mediated inflammation. In the liver, however, the IL-28A induced Th1 cytokine response contributes to inflammation in T cell mediated hepatitis. IL-28A additionally exhibits anti-tumor activity, in part by enhancing IL-12 dependent anti-tumor CTL responses. In contrast, it is upregulated in invasive bladder cancer where it promotes tumor cell migration.
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, Neut |
| Source: | NS0 |
| Accession #: | NP_001019844 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #244716 |
| Applications: | Neut |
| Reactivity: | Mouse |
| Details: | Sheep IgG Polyclonal |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #884103R |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #884103R |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #248526 |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #625616 |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #625616 |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #248526 |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #244716 |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #244716 |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #884103R |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #248512 |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #248512 |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #884136R |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #884136R |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #884136R |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #625616 |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #884113R |