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12 results for "IL-12 Proteins and Enzymes" in Products
IL-12 Proteins and Enzymes
IL-12 (Interleukin-12) is a heterodimeric cytokine that consists of a p35 and a p40 subunit. p40 is also a subunit of the cytokine IL-23. IL-12 enhances the cytotoxic activity and induces IFN-gamma production in NK cells, T cells, and dendritic epidermal T cells, and it promotes a Th1 biased immune response. It signals through a receptor complex composed of IL-12 R beta 1 and IL-12 R beta 2. Both homodimeric p40, and IL-23 can bind to the IL-12 receptor, serving as non-signaling antagonists.
GS Linker, Defined heterodimer stoichiometry.
Reactivity:
Human
Source:
HEK293
Accession #:
P29460.1 (IL-12p40), P29459.2 (IL-12p35)
Applications:
Bioactivity
Reactivity:
Mouse
Source:
Sf 21 (baculovirus)
Accession #:
P43432 (p40) & NP_032377 (p35)
Applications:
Bioactivity
Reactivity:
Feline
Source:
Sf 21 (baculovirus)
Accession #:
O02744 (p40) & O02743 (p35)
Applications:
Bioactivity
Reactivity:
Canine
Source:
CHO
Accession #:
Q28268 (p40) & Q28267 (p35)
Applications:
Bioactivity
Reactivity:
Porcine
Source:
CHO
Accession #:
Q28938 (p40) & Q29053 (p35)
Applications:
Bioactivity
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
WB, B/N
GS Linker, Defined heterodimer stoichiometry.
Reactivity:
Cynomolgus Monkey
Source:
HEK293
Accession #:
NP_001274204 (IL-12p40) & XP_005546300 (IL-12p35)
Applications:
Bioactivity
Reactivity:
Rhesus Macaque
Source:
CHO
Accession #:
P48095 (p40) & NP_001038199 (p35)
Applications:
Bioactivity
GS Linker, Defined heterodimer stoichiometry.
Reactivity:
Mouse
Source:
NS0
Accession #:
P43432, P43431
Applications:
Bioactivity
Reactivity:
Rat
Source:
Sf 21 (baculovirus)
Accession #:
NP_072133 (p40) & Q9R103 (p35)
Applications:
Bioactivity
Reactivity:
Human
Source:
HEK293
Accession #:
P29459.2
Applications:
Bioactivity
Reactivity:
Human
Source:
HEK293
Accession #:
P29459.2
Applications:
Bioactivity