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2 results for "IL-1 alpha/IL-1F1 Small Molecules and Peptides" in Products

IL-1 alpha/IL-1F1 Small Molecules and Peptides

IL-1 alpha (Interleukin-1 alpha) is a cytokine that is induced during microbial exposure and promotes the release of multiple inflammatory mediators and acute phase proteins. It also supports hematopoietic stem cell expansion, promotes neutrophil mobilization from the bone marrow, and promotes osteoclast formation. IL-1 alpha signals through a receptor complex composed of IL-1 RI and IL-1 RAcP. It also binds the decoy receptor IL-1 RII which associates with IL-1 RAcP but does not transduce signalling.

 

Potent, selective human type I IL-1 receptor antagonist

Purity:
≥95%
Potent, selective human type I IL-1 receptor antagonist

Active metabolite binds CPSF3; Pro-drug

Alternate Names:
TO-207
Chemical Name:
N-[3,5-Dichloro-2-hydroxy-4-[2-(4-methyl-1-piperazinyl)ethoxy]benzoyl]-L-phenylalanine ethyl ester dihydrochloride
Purity:
≥98%
Active metabolite binds CPSF3; Pro-drug
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