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56 results for "Huntingtin" in Products

Huntingtin Products

Huntingtin protein (Htt) is a 348 kDa protein product of Huntington's disease (HD, IT15) gene. Huntington's disease is a neurodegenerative disorder caused by a mutation on the HD gene, producing a polyglutamin (polyQ) expansion on the N-terminus of Htt. The mutant Htt leads to cytotoxicity in the striatal neuron (1). This cytotoxicity is modulated by proteolytic cleavage with caspases and calpains, producing N-terminal polyQ fragments. A phosphorylation of Htt may also regulate the cleavage and ...

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Recombinant Monoclonal Antibody

Recombinant Monoclonal Antibody

Recombinant Monoclonal Antibody

Catalog #: NBP3-51390

Recombinant Monoclonal Antibody

Catalog #: NBP3-24905PEP
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