3 results for "HSP90 Inhibitors" in Products
HSP90 Inhibitors Products
Hsp90 (90 kDa heat shock protein) is a molecular chaperone that aids protein folding and quality control for a large number of "client" proteins. Functional Hsp90 operates as dimer and has intrinsic ATPase activity. The Hsp90 dimer acts in concert with other chaperones (e.g. Hsp70) and is regulated by a number of co-chaperones/accessory proteins (e.g. Hop, cdc37).
Hsp90 has been shown to interact with >100 proteins and some notable clients include kinases (e.g. Raf-1), nuclear ...
Selective Hsp90 inhibitor
| Alternate Names: | NSC 330507,17-(Allylamino)-17-demethoxygeldanamycin,Tanespimycin |
| Chemical Name: | 17-Demethoxy-17-(2-propenylamino)geldanamycin |
| Purity: | ≥98% (HPLC) |
High affinity, potent and selective Hsp90 inhibitor
| Chemical Name: | 5-[2-Amino-4-chloro-7-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-methyl-4-pentyn-2-ol |
| Purity: | ≥98% (HPLC) |
Hsp90 inhibitor
| Chemical Name: | 4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-methyl-1H-pyrazol-3-yl]-6-ethyl-1,3-benzenediol |
| Purity: | ≥98% (HPLC) |
