HIST2H3A: Proteins and Enzymes

HIST2H3A is 136 amino acids long, weighs approximately 15 kDa, and the gene codes for a part of a group of basic nuclear proteins called histones, which are responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Current studies are being done on several diseases and disorders including systemic lupus erythematosus, lupus erythematosus, hepatocellular carcinoma, adenocarcinoma, carcinoma, leukemia, and neuronitis. HIST2H3A has also been shown to have interactions with HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, and HIST1H4E in pathways such as the IL-4 signaling, amyloids, hemostasis, meiosis, meiotic recombination, and systemic lupus erythematosus pathways.