Having trouble trying to find the right product? Chat with our scientists below - we're here to help!
Select a category to see relevant filters and products
12 results for "Hedgehog Signaling Inhibitors" in Products
Hedgehog Signaling Inhibitors
Inhibitor of hedgehog (Hh) signaling; antagonizes smoothened activity
Chemical Name:
N-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-4-(phenylmethyl)-1-piperazinamine
Purity:
≥98%
Inhibitor of Hedgehog (Hh) signaling
Chemical Name:
(2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-Octadecahydro-3',6',10,11b-tetramethylspiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-3-ol
Purity:
≥97%
GLI antagonist; inhibits Hedgehog (Hh) signaling
Chemical Name:
2,2'-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethylbenzenamine
Purity:
≥98%
Inhibitor of Hedgehog (Hh) signaling. Inhibits Δ7-dehydrocholesterol reductase
Chemical Name:
trans-N,N-bis[2-Chlorophenylmethyl]-1,4-cyclohexanedimethanamine dihydrochloride
Purity:
≥98%
High affinity and selective Smoothened (Smo) receptor antagonist
Chemical Name:
1-[4-(5'-Chloro-3,5-dimethyl[2,4'-bipyridin]-2'-yl-1-piperazinyl]-3-(methylsulfonyl)-1-propanone hydrochloride
Purity:
≥98%
Potent Smo antagonist
Chemical Name:
N,N'-1,4-Phenylenebis[2,5-dichlorobenzamide]
Purity:
≥98%
Inhibitor of Hedgehog (Hh) signaling; inhibits cytoplasmic dynein
Chemical Name:
Ethyl 4-(4-(diethylamino)phenyl)-2-((2,4-difluorophenyl)amino)thiazole-5-carboxylate
Purity:
≥98%
Potent Smo antagonist
Alternate Names:
glasdegib,PF-913
Chemical Name:
1-((2R,4R)-2-(1H-Benzimidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea maleate salt
Purity:
≥98%
Hedgehog signaling inhibitor; dynein inhibitor
Chemical Name:
2-[1-(4-Chlorophenyl)cyclopropyl]-4,5-dihydro-7-iodo-5-oxopyrazolo[1,5-a]quinazoline-3-carbonitrile
Purity:
≥98%
Potent hedgehog pathway inhibitor
Chemical Name:
2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide
Purity:
≥98%
Potent Smo antagonist
Alternate Names:
glasdegib,PF-913
Chemical Name:
1-((2R,4R)-2-(1H-Benzimidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea maleate salt
Purity:
≥98%
BET bromodomain Degrader (PROTAC®); also potent Hedgehog pathway inhibitor
Chemical Name:
2-Methoxyethyl 4-(3-((1-(6-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)hexyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-7-(2-methoxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate
Purity:
≥98%
