GPR39: Small Molecules and Peptides
GPR39 is a seven transmembrane G protein coupled glycoprotein that is a member of the ghrelin receptor family. GPR39 is expressed in the stomach, small intestine and areas of the brain including the hypothalamus; its ligand is the ghrelin-associated peptide, obestatin. Obestatin decelerates gastric emptying and decreases intestinal contractility in mice, couteracting the effects of ghrelin. GPR39 has not been shown to be internalized upon ligand binding.
1 result for "GPR39 Small Molecules and Peptides" in Products
1 result for "GPR39 Small Molecules and Peptides" in Products
GPR39: Small Molecules and Peptides
GPR39 is a seven transmembrane G protein coupled glycoprotein that is a member of the ghrelin receptor family. GPR39 is expressed in the stomach, small intestine and areas of the brain including the hypothalamus; its ligand is the ghrelin-associated peptide, obestatin. Obestatin decelerates gastric emptying and decreases intestinal contractility in mice, couteracting the effects of ghrelin. GPR39 has not been shown to be internalized upon ligand binding.
Potent and selective GPR39 agonist
| Chemical Name: | N-[3-Chloro-4-[[[2-(methylamino)-6-(2-pyridinyl)-4-pyrimidinyl]amino]methyl]phenyl]methanesulfonamide |
| Purity: | ≥98% (HPLC) |
