GLI-2: Small Molecules and Peptides
GLI family proteins are zinc finger transcription factors best known for regulating the expression of gene targets of Hedgehog (Hh) signaling. They share homology with the Drosophila Ci protein, which serves as a mediator of Hh responses in the fly. GLI3 functions primarily as a repressor of Hh target gene expression, while GLI-1 and GLI-2 are activators that promote Hh signaling.
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1 result for "GLI-2 Small Molecules and Peptides" in Products
GLI-2: Small Molecules and Peptides
GLI family proteins are zinc finger transcription factors best known for regulating the expression of gene targets of Hedgehog (Hh) signaling. They share homology with the Drosophila Ci protein, which serves as a mediator of Hh responses in the fly. GLI3 functions primarily as a repressor of Hh target gene expression, while GLI-1 and GLI-2 are activators that promote Hh signaling.
GLI antagonist; inhibits Hedgehog (Hh) signaling
| Chemical Name: | 2,2'-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethylbenzenamine |
| Purity: | ≥98% (HPLC) |
