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6 results for "GDNF" in Products

GDNF Products

GDNF (Glial Cell Line-derived Neurotrophic Factor) is a secreted protein that promotes the survival of motoneurons, midbrain dopaminergic neurons, Purkinje cells, and sympathetic neurons. It is produced by Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes, and skeletal muscle cells. GDNF binding to GFR alpha 1 induces the recruitment of Ret, NCAM-1/CD56, various integrins, Syndecan-3, or N-Cadherin. GDNF-based therapies show promise in several neurodegenerative disorders, particularly Parkinson’s disease.

Reactivity:
Human, Rat
Details:
Goat IgG Polyclonal
Applications:
IHC, WB, B/N
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #27106
Applications:
WB, ELISA(Cap), ELISA(Det)

Recombinant Monoclonal Antibody.

Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #27106R
Applications:
ELISA(Cap), ELISA(Det)
Reactivity:
Rat
Details:
Goat IgG Polyclonal
Applications:
ELISA
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #27165
Applications:
ICC/IF
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #27109
Applications:
ELISA
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