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7 results for "FGFR2 beta" in Products

FGFR2 beta Products

FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGFR1 through 5. FGFRs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGFR1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGFR5 does not. Multiple forms of FGFR1, 2, and 3 are generated by alternative splicing.

Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
WB, ICC/IF
Detection of Human Phospho- FGF R1-4 (Y653/Y654) antibody by Western Blot.
(5)
Reactivity:
Mouse
Source:
Sf 21 (baculovirus)
Accession #:
AAI72174
Applications:
Bioactivity
R&D Systems Recombinant Proteins and Enzymes
Reactivity:
Human
Source:
Sf 21 (baculovirus)
Accession #:
NP_001138391
Applications:
Bioactivity
R&D Systems Recombinant Proteins and Enzymes
Reactivity:
Human
Source:
NS0
Accession #:
NP_001138387
Applications:
Bioactivity
R&D Systems Recombinant Proteins and Enzymes
Reactivity:
Mouse
Source:
NS0
Accession #:
NP_034337.2
Applications:
Bioactivity
R&D Systems Recombinant Proteins and Enzymes

Potent VEGFR, PDGFR and FGFR inhibitor

Chemical Name:
Methyl (Z)-3-[[[4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene]-2-oxoindoline-6-carboxylate
Purity:
≥98%
Potent VEGFR, PDGFR and FGFR inhibitor

Potent VEGFR, PDGFR and FGFR inhibitor

Chemical Name:
Methyl (Z)-3-[[[4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene]-2-oxoindoline-6-carboxylate
Purity:
≥98%
Potent VEGFR, PDGFR and FGFR inhibitor
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