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FGF basic/FGF2/bFGF Products

FGF basic/FGF2/bFGF is a growth factor that functions in angiogenesis, wound healing, tissue repair, learning and memory, and the morphogenesis of heart, bone, and brain. It is upregulated in response to inflammatory stimuli and in many tumors. FGF basic/FGF2/bFGF binds to FGFR1c and 2c. Its bioactivity is modulated by a number of other binding partners including heparin, Integrin alpha V beta 3, soluble FGFR1, FGF-BP, free gangliosides, Thrombospondin, Pentraxin 3/TSG-14, Fibrinogen, alpha 2-Macroglobulin, PDGF, and CXCL4/PF4. These molecules act as cellular coreceptors or adhesion partners, extracellular matrix decoys or reservoirs, and soluble scavengers or chaperones. In particular, the interaction of FGF basic/FGF2/bFGF with cell surface heparan sulfate proteoglycans (HSPG) is required for the binding and activation of FGF receptors.

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457 results for "FGF basic/FGF2/bFGF" in Products

457 results for "FGF basic/FGF2/bFGF" in Products

FGF basic/FGF2/bFGF Products

FGF basic/FGF2/bFGF is a growth factor that functions in angiogenesis, wound healing, tissue repair, learning and memory, and the morphogenesis of heart, bone, and brain. It is upregulated in response to inflammatory stimuli and in many tumors. FGF basic/FGF2/bFGF binds to FGFR1c and 2c. Its bioactivity is modulated by a number of other binding partners including heparin, Integrin alpha V beta 3, soluble FGFR1, FGF-BP, free gangliosides, Thrombospondin, Pentraxin 3/TSG-14, Fibrinogen, alpha 2-Macroglobulin, PDGF, and CXCL4/PF4. These molecules act as cellular coreceptors or adhesion partners, extracellular matrix decoys or reservoirs, and soluble scavengers or chaperones. In particular, the interaction of FGF basic/FGF2/bFGF with cell surface heparan sulfate proteoglycans (HSPG) is required for the binding and activation of FGF receptors.

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Sensitivity: 3 pg/mL
Applications: ELISA
Assay Range: 10 - 640 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma)
Human FGF basic ELISA Standard Curve
(2)
Source: E. coli
Accession #: NP_001997
Applications: BA
Recombinant Human FGF basic/FGF2/bFGF (145 aa) Protein Bioactivity
(3)

Intended for preclinical researchers who may transition to GMP FGF basic/FGF2 for their clinical work, Analyzed by SEC-MALS

Source: E. coli
Accession #: NP_001997.5
Applications: BA
(2)

Analyzed by SEC-MALS

Source: E. coli
Accession #: NP_001997
Applications: BA, BA
(3)
Sensitivity: 0.07 pg/mL
Applications: ELISA
Assay Range: 0.313 - 20 pg/mL (Serum, EDTA Plasma, Citrate Plasma, Urine)
Human FGF basic ELISA Standard Curve
(2)

Analyzed by SEC-MALS

Source: E. coli
Accession #: NP_001997.5
Applications: BA
(4)
Source: E. coli
Accession #: P15655
Applications: BA
Recombinant Mouse FGF basic/FGF2/bFGF Protein Bioactivity
(2)
Source: E. coli
Accession #: NP_001997
Applications: BA
Recombinant Human FGF basic/FGF2/bFGF (157 aa) Protein Bioactivity
(2)
Assay Range: 15.6 - 1,000 pg/mL
Applications: ELISA
Human FGF basic ELISA Standard Curve
Source: E. coli
Accession #: NP_001997.5
Applications: BA
(4)
Source: E. coli
Accession #: P13109
Applications: BA
R&D Systems Recombinant Proteins and Enzymes
Sensitivity: 3.68 pg/mL
Applications: ELISA
Assay Range: 15.6 - 1,000 pg/mL (Cell Culture Supernates, Tissue Lysates, Serum, EDTA Plasma)
Mouse/Rat FGF basic ELISA Standard Curve
(2)
Source: E. coli
Accession #: P03969
Applications: BA
R&D Systems Recombinant Proteins and Enzymes
Source: Bovine Brain
Applications: BA

Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.

Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.

Reactivity: Bovine
Details: Rabbit IgG Polyclonal
Applications: WB, Neut
Cell Proliferation Induced by FGF basic/FGF2/bFGF and Neutralization by Bovine FGF basic/FGF2/bFGF Antibody.
Assay Range: 46.9 - 3,000 pg/mL
Applications: ELISA
Mouse FGF basic ELISA Standard Curve

Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.

Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.

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