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5 results for "FGF-19 ELISA Kits" in Products
FGF-19 ELISA Kits
FGF-19 (Fibroblast Growth Factor-19) is a secreted heparin-binding protein in the endocrine subfamily of FGFs that also includes FGF-21 and FGF-23. It is produced by epithelial cells of the ileal intestine in response to bile acids and signals through a receptor complex of FGF R4 and Klotho-beta in the liver. FGF-19 suppresses bile acid synthesis and enhances hepatic protein and glycogen synthesis. Dysregulalted FGF-19 activity is associated with the development of hypercholesterolemia, gall stones, bile acid induced diarrhoea (BAD), hepatocellular cancer, colon cancer, and metabolic syndrome.
Reactivity:
Human
Assay Range:
15.6-1000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)
Applications:
ELISA
Reactivity:
Human
Assay Range:
15.6-1000 pg/mL
Applications:
ELISA
Reactivity:
Rat
Assay Range:
15.625 - 1000 pg/mL (example only; lot dependent)
Applications:
ELISA
Reactivity:
Mouse
Assay Range:
31.2 - 2000 pg/mL (example only; lot dependent)
Applications:
ELISA
Reactivity:
Mouse
Assay Range:
31.2 - 2000 pg/mL (example only; lot dependent)
Applications:
ELISA