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1 result for "ErbB4/Her4" in Products

ErbB4/Her4 Products

ErbB4, also known as Her4, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for the EGF family of growth factors. ErbB4 ligands include the neuregulins, betacellulin and heparin-binding EGF-like growth factor (HB-EGF).

Potent dual specificity EGFR/HER2 inhibitor; active in vivo

Alternate Names:
BIBW2992
Chemical Name:
(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide dimaleate
Purity:
≥98%
Potent dual specificity EGFR/HER2 inhibitor; active in vivo
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