12 results for "ErbB2/Her2" in Products
ErbB2/Her2 Products
ErbB2, also called Neu and Her2, is a transmembrane glycoprotein in the ErbB family of tyrosine kinase receptors for EGF superfamily growth factors. ErbB2 is widely expressed in epithelial cells and over-expressed in a large number of breast carcinomas. ErbB2 has no identified ligands but heterodimerizes with ErbB1/EGF R, ErbB3, or ErbB4 to form higher affinity signaling complexes. The protease ADAM10 releases a 110 kDa soluble fragment of ErbB2 from the cell surface. ErbB2 plays roles in ...
EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor
Negative control for PP 2 (Cat. No. 1407)
Potent and selective dual ErbB2 (HER-2) and EGFR inhibitor
Potent dual EGFR/ErbB2 inhibitor; orally active
Potent ErbB receptor family inhibitor
Potent and selective ErbB2 inhibitor
Potent EGFR and VEGFR inhibitor
Potent irreversible pan ErbB inhibitor
Potent dual specificity EGFR/HER2 inhibitor; active in vivo
Highly potent EGFR and ErbB2 inhibitor; inhibts wild type and mutated receptors
Potent HER2 receptor tyrosine kinase and EGFR kinase inhibitor
Potent and selective ErbB2 inhibitor
