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7 results for "E-Cadherin Proteins and Enzymes" in Products
E-Cadherin Proteins and Enzymes
E-Cadherin/Cadherin-1 (ECAD) Is a transmembrane cell adhesion protein. It forms homophilic clusters between epithelial cells and is a critical component of adherens junctions. These junctions are critical for the maintenance of the epithelial barrier and epithelial tissue homeostasis. Decreased E-Cadherin is associated with physiological and pathological epithelial-to-mesenchymal transition (EMT) and cell migration, and E-Cadherin loss contributes to cancer metastasis. The shed ECD is released as a soluble factor that enhances cancer cell motility and EGFR-dependent survival and proliferation.
Reactivity:
Human
Source:
HEK293
Accession #:
P12830
Applications:
Bioactivity
Analyzed by SEC-MALS
Reactivity:
Mouse
Source:
NS0
Accession #:
P09803
Applications:
Bioactivity
Reactivity:
Rat
Source:
NS0
Accession #:
Q9R0T4
Applications:
Bioactivity
Reactivity:
Human
Source:
HEK293
Accession #:
P12830.3
Applications:
Bioactivity
Catalog #:
NBP1-84588PEP
Reactivity:
Human
Source:
E. coli
Applications:
AC
Catalog #:
NBP2-34475PEP
Reactivity:
Human
Source:
E. coli
Applications:
AC
Catalog #:
NBP2-34476PEP
Reactivity:
Human
Source:
E. coli
Applications:
AC