167 results for "COMP/Thrombospondin-5" in Products
COMP/Thrombospondin-5 Products
COMP (Cartilage Oligomeric Matrix Protein), also known as Thrombospondin-5, is a multidomain calcium binding protein that associates with other extracellular matrix molecules. COMP associates into disulfide-linked homopentamers with a central hub and peripheral globular domains connected by flexible strands. An axial pore is formed by the coiled coil assembly and binds vitamin D3 which is involved in bone and cartilage metabolism. An RGD sequence in the third TSP type-3 repeat mediates chondrocyte attachment via Integrins a5b1 or aVb3. COMP is upregulated in rheumatoid arthritis and osteoarthritis, hepatocellular carcinomas, chronic pancreatitis, and pancreatic carcinomas. Several mutations in COMP are associated with skeletal dysplasias.
| Assay Range: | 39.1 - 2,500 pg/mL |
| Applications: | ELISA |
| Applications: | Simple Plex |
Simple Plex cartridges are custom built to fit your needs. Choose from over 350 assays spanning human, mouse, rat, and non-human primate. Just select your sample type, cartridge size (16, 32, or 72 samples), and add up to 8 analytes per cartridge.
| Applications: | Ctrl, Simple Plex |
| Sensitivity: | 0.036 ng/mL |
| Applications: | ELISA |
| Assay Range: | 0.156 - 10 ng/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma) |
| Applications: | ELISA |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #360215 |
| Source: | NS0 |
| Accession #: | P49747 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #2127-F5 |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #360215 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #2127-F5 |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #2127-F5 |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #360215 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #360215 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #360215 |
| Applications: | WB |