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CD8 Products

CD8, also known as Ly-2 or Leu-2, is a heterodimeric glycoprotein (alpha and beta subunits) that functions in conjunction with the T cell receptor in the recognition of MHC class I/peptide complexes. CD8 alpha is expressed on double positive (CD4+8+) thymocytes and mature CD8+ cytolytic T cells, intraepithelial lymphocytes, some gamma-delta T cells, subsets of thymic and splenic dendritic cells, and peritoneal mast cells. It can form disulfide linked homodimers or heterodimers with CD8 beta. Thymic CD8+ DC express primarily alpha-beta heterodimers, while splenic CD8+ DC primarily express alpha-alpha homodimers. CD8 alpha+ DC can present viral antigenic peptides in complex with MHC I and prime CTL responses.

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1082 results for "CD8" in Products

1082 results for "CD8" in Products

CD8 Products

CD8, also known as Ly-2 or Leu-2, is a heterodimeric glycoprotein (alpha and beta subunits) that functions in conjunction with the T cell receptor in the recognition of MHC class I/peptide complexes. CD8 alpha is expressed on double positive (CD4+8+) thymocytes and mature CD8+ cytolytic T cells, intraepithelial lymphocytes, some gamma-delta T cells, subsets of thymic and splenic dendritic cells, and peritoneal mast cells. It can form disulfide linked homodimers or heterodimers with CD8 beta. Thymic CD8+ DC express primarily alpha-beta heterodimers, while splenic CD8+ DC primarily express alpha-alpha homodimers. CD8 alpha+ DC can present viral antigenic peptides in complex with MHC I and prime CTL responses.

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Recombinant Monoclonal Antibody

Recombinant Monoclonal Antibody

Recombinant Monoclonal Antibody

Recombinant Monoclonal Antibody

Recombinant Monoclonal Antibody

Recombinant Monoclonal Antibody

Recombinant Monoclonal Antibody

Recombinant Monoclonal Antibody

Recombinant Monoclonal Antibody

Recombinant Monoclonal Antibody

Analyzed by SEC-MALS.

Clone RPA-T8 was used by HLDA to establish CD designation.

Analyzed by SEC-MALS.

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