20 results for "Caspase Inhibitors Small Molecules and Peptides" in Products
Caspase Inhibitors: Small Molecules and Peptides
Caspases (cysteinyl aspartate proteases) are involved in the signal transduction pathways of apoptosis, necrosis and inflammation. These enzymes can be divided into two major classes - initiators and effectors. The initiator isoforms (caspases-1,-4,-5,-8,-9,-10,-11,-12) are activated by, and interact with, upstream adaptor molecules through protein-protein interaction domains known as CARD and DED.
Effector caspases (-3,-6,-7) are responsible for cleaving downstream substrates and are ...
| Chemical Name: | Benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone |
| Purity: | ≥95% (HPLC) |
| Chemical Name: | N-[2-(1,1-Dimethylethyl)phenyl]-2-oxoglycyl-N-[(1S)-1-(carboxymethyl)-2-oxo-3-(2,3,5,6-tetrafluorophenoxy)propyl]-L-alaninamide |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | Ethyl 2[(2-chlorophenyl)(hydroxy)methyl]acrylate |
| Purity: | ≥98% (HPLC) |
| Alternate Names: | Belnacasan |
| Chemical Name: | N-(4-Amino-3-chlorobenzoyl)-3-methyl-L-valyl-N-[(2R,3S)-2-ethoxytetrahydro-5-oxo-3-furanyl]-L-prolinamide |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 4-[[4-Oxo-2-thioxo-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]benzoic acid |
| Purity: | ≥98% (HPLC) |
