308 results for "Caspase-8" in Products
Caspase-8 Products
Caspase-8, also known as MCH5, FLICA and MACH alpha 1, is a 28 kDa member of the peptidase C14A family of enzymes. It is widely expressed and is considered an initiating caspase for the apoptotic cascade. Caspase-8 acts on a wide variety of substrates including Pro-Caspases-3, -4, -6, -7, -9 and -10, c-FLIPL and Pro-Caspase‑8 itself. Caspase-8 is recruited to the death-inducing signaling complex (DISC) that forms around the death domains of the oligomerized receptors. Multiple rounds of cleavage generate Caspase-8 p10 and p18 which heterodimerize and then associate into the active tetrameric enzyme containing two p10 and two p18 subunits.
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, Simple Western |
Conjugate
Catalog #
| Reactivity: | Human, Primate, Primate - Macaca mulatta (Rhesus Macaque), Insect - Drosophila melanogaster |
| Details: | Mouse IgG1 Monoclonal Clone #90A992 |
| Applications: | IHC, WB, Flow, CyTOF-ready, Simple Western |
![Western Blot: Caspase-8 Antibody (90A992)BSA Free [NB100-56527]](https://resources.bio-techne.com/images/products/Caspase-8-Antibody-90A992-Western-Blot-NB100-56527-img0018.jpg "Western Blot: Caspase-8 Antibody (90A992)BSA Free [NB100-56527]")
Conjugate
Catalog #
Forumulation
Catalog #
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #746109 |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, KO |
Conjugate
Catalog #
| Source: | E. coli |
| Accession #: | Q14790 |
| Applications: | EnzAct |
Conjugate
Catalog #
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #84131 |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #84131 |
| Applications: | WB |
Conjugate
Catalog #
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
Conjugate
Catalog #
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
Conjugate
Catalog #
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, KO |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #84131 |
| Applications: | WB |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #84131 |
| Applications: | WB |
Conjugate
Catalog #
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, KO |
Conjugate
Catalog #
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
Conjugate
Catalog #
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, KO |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #746109 |
| Applications: | ICC |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #746109 |
| Applications: | ICC |
Conjugate
Catalog #