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3 results for "Caspase-3" in Products
Caspase-3 Products
Caspase-3 is a widely expressed dimeric peptidase that is the major executioner caspase, the primary downstream mediator of apoptotic-associated proteolysis. Caspase-3 cleaves multiple substrates including PARP, proIL-16, PKC-gamma and -delta, proCaspases-6, -7, and -9, and beta-Catenin. Normally, it is an inactive, exclusively cytosolic homodimer. During apoptosis, however, proCaspase-3 is activated by cleavage into p20 and p12 subunits, and the p20 subunit is trimmed to yield a p17 subunit. Active Caspase-3 contains two p17 and two p12 subunits.
Reactivity:
Human, Mouse, Rat, Porcine, Chicken, +2 More
Details:
Mouse IgG1 kappa Monoclonal Clone #31A1067
Applications:
KO, IHC, WB, Flow, ICC/IF, + 5 More
Reactivity:
Human, Mouse
Details:
Goat IgG Polyclonal
Applications:
KO, WB, Simple Western, IP
Reactivity:
Human, Mouse, Rat, Porcine, Chicken, +2 More
Details:
Mouse IgG1 kappa Monoclonal Clone #31A1067
Applications:
KO, IHC, WB, Flow, ICC/IF, + 5 More