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1 result for "Bcl-6 Small Molecules and Peptides" in Products

Bcl-6 Small Molecules and Peptides

Bcl-6 (B-cell lymphoma protein 6; also ZFP51, LAZ-3 and Bcl-5) is an 80 kDa member of the Kruppel-like family of zinc finger proteins. It is expressed in germinal center B cells, neutrophils, monocytes, and immature dendritic cells, and serves as a potent transcriptional repressor of genes such as p53. Human Bcl-6 is 706 amino acids (aa) in length and contains an N-terminal BTB/POZ protein interaction domain (aa 32-99) and a series of six C2H2-type C-terminal zinc finger domains that bind DNA ...

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High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor

Chemical Name:
4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide
Purity:
≥98%
High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor
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