5-HT5A: Small Molecules and Peptides
The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. 5-HT5A belongs to the G protein-coupled receptor 1 family. 5-HT5A is also a member of the serotonin receptor family. It is a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G proteins. 5-HT5A has been shown to function in part through the regulation of intracellular Ca2+ mobilization.
4 results for "5-HT5A Small Molecules and Peptides" in Products
4 results for "5-HT5A Small Molecules and Peptides" in Products
5-HT5A: Small Molecules and Peptides
The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. 5-HT5A belongs to the G protein-coupled receptor 1 family. 5-HT5A is also a member of the serotonin receptor family. It is a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G proteins. 5-HT5A has been shown to function in part through the regulation of intracellular Ca2+ mobilization.
Endogenous 5-HT receptor agonist
| Alternate Names: | 5-Hydroxytryptamine,5-HT |
| Chemical Name: | 3-(2-Aminoethyl)-1H-indol-5-ol hydrochloride |
| Purity: | ≥98% (HPLC) |
5-HT1 agonist; also has high affinity for 5-ht5a and 5-HT7
| Alternate Names: | AH-21467,5-CT |
| Purity: | ≥99% (HPLC) |
Potent and selective 5-HT7 antagonist; brain penetrant
| Chemical Name: | (2R)-1-[(3-Hydroxyphenyl)sulfonyl]-2-[2-(4-methyl-1-piperidinyl)ethyl]pyrrolidine hydrochloride |
| Purity: | ≥98% (HPLC) |
Selective 5-ht5a antagonist
| Chemical Name: | N-[2-(Dimethylamino)ethyl]-N-[[4'-[[(2-phenylethyl)amino]methyl][1,1'-biphenyl]-4-yl]methyl]cyclopentanepropanamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
