2 results for "11 beta-HSD Inhibitors" in Products
11 beta-HSD Inhibitors Products
The isozymes 11β-HSD1 and 11β-HSD2, both 11β-Hydroxysteroid Dehydrogenases (11β-HSD), catalyze the interconversion of cortisol (corticosterone in rodents) and cortisone (11-dehyrodocorticosterone). 11β-HSD1 converts cortisone to cortisol, the active hormone; and 11β-HSD2 converts cortisol to cortisone, the inactive form.
Cortisol is initially synthesized and released by the adrenal glands under the strict control of adrenocorticotrophic hormone (ACTH). Levels vary ...
Potent and selective 11β-hydroxysteroid dehydrogenase inhibitor
| Chemical Name: | N-(6-Amino-2-pyridinyl)-4'-cyano-[1,1'-biphenyl]-4-sulfonamide |
| Purity: | ≥98% (HPLC) |
Gap junction blocker. Also inhibitor of 11 β-hydroxysteroid dehydrogenase
| Chemical Name: | (3β,20β)-3-(3-Carboxy-1-oxopropoxy)-11-oxoolean-12-en-29-oic acid disodium |
| Purity: | ≥98% (HPLC) |
