RNAscope™ Technology Citations

At Bio-Techne, we're advancing the fields of spatial biology and spatial multiomics with innovative RNAscope ISH technology. RNAscope ISH technology has paved the way for researchers to visualize RNA within spatial context. Our innovative portfolio enables scientists to reveal unique insights into mRNA, long-non-coding RNA, micro RNA, small-interfering RNA, therapeutic oligonucleotides, viral RNA and protein expression. As a result, our RNAscope technology has been cited in over 11,000 high-impact journal publications across multiple applications and disciplines. Use this citation database to find published articles that utilized RNAscope spatial multiomics technology.

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Article:
Regulation of neurogenesis and neuronal migration by Rrm2 and Timp3 following seizures
(2025) Neurobiology of disease 215:107094.
Author: Adeyeye, AO et al.
Varma, P,
Enerlan, N,
Coppin, M,
Hsieh, J,
 Publication Date: Wed, 10/15/2025 - 00:00 PMID: 40930429
Product Code: 323100 Assay: RNAscope Multiplex Fluorescent V2 assay Species: Mouse
Gene Name: Timp3; Rrm2;  DCX  Sample Type: Fixed Frozen Research Area: Neuroscience; Development
Article:
HDAC6 and TDP-43 promote autophagy impairment in amyotrophic lateral sclerosis
(2025) Neurobiology of disease 215:107079.
Author: Bordoni, M et al.
Scarian, E,
Jacchetti, E,
Viola, C,
Diamanti, L,
Dragoni, F,
Di Gerlando, R,
Rizzo, B,
Raimondi, MT,
Gagliardi, S,
Pansarasa, O,
 Publication Date: Wed, 10/15/2025 - 00:00 PMID: 40912409
Product Code: 323100 Assay: RNAscope Multiplex Fluorescent V2 assay Species:
Gene Name: Sample Type: Fixed Research Area:
Article:
Immune and HPV landscape in oral multiple primary cancers compared to single primary cancer
(2025) Oral oncology 169:107646.
Author: Zhou, X et al.
Zhang, J,
Lou, Y,
Li, W,
Xu, Z,
Zhang, H,
Li, T,
 Publication Date: Wed, 10/01/2025 - 00:00 PMID: 40966845
Product Code: 322300 Assay: RNAscope 2.5 HD assay- BROWN Species: Human
Gene Name: E6; E7; HPV 16; HPV 18 Sample Type: FFPE Research Area: Cancer; HPV
Article:
Clinicopathological and prognostic exploratory study of primary metaplastic squamous cell carcinoma of the breast
(2025) PLoS ONE 20 (9):e0333347-e0333347.
Author: Zhang, F et al.
Chengmin, Z,
Yang, Y,
Li, J,
Ma, Y,
Dai, J,
 Publication Date: Tue, 09/30/2025 - 00:00 PMID: 41026783
Product Code: 322360 Assay: RNAscope 2.5 HD assay- RED Species: Human
Gene Name: HPV Sample Type: FFPE Research Area: Cancer
Article:
GLUT1 Expression Patterns in Verruciform Acanthotic Vulvar Squamous Intraepithelial Neoplasia, HPV-independent p53 Wild-Type Squamous Cell Carcinoma and Benign Vulvar Lesions
(2025) Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc:100900.
Author: Zhang, G et al.
Soslow, RA,
Yang, B,
 Publication Date: Mon, 09/29/2025 - 00:00 PMID: 41033580
Product Code: 322350 Assay: RNAscope 2.5 HD assay- RED Species: Human
Gene Name:  E6; E7 Sample Type: FFPE Research Area: HPV
Article:
T cell-mediated clearance of porcine reproductive and respiratory syndrome virus (PRRSV) from the lung characterized by machine learning analysis in vaccinated and unvaccinated pigs
(2025) Vaccine 65:127793.
Author: Noel, A et al.
Zhang, J,
Nedumpun, T,
Sitthicharoenchai, P,
Guo, B,
Phillips, R,
Kunze, M,
Gomez-Duran, O,
Groeltz-Thrush, J,
Rahe, E,
Rahe, MC,
 Publication Date: Sat, 09/27/2025 - 00:00 PMID: 41016230
Product Code: 322350 Assay: RNAscope 2.5 HD assay- RED Species: pig
Gene Name: PRRSV Sample Type: FFPE Research Area: Infectious Disease; Veterinary; Immunology
Article:
Craniofacial-specific transcriptomics uncovers novel genes underlying jaw divergence in dietary specialist pupfishes
(2025) Genetics.
Author: Palominos, MF et al.
Muhl, V,
Martin, CH,
 Publication Date: Fri, 09/26/2025 - 00:00 PMID: 41001823
Product Code: 322100 Assay: RNAscope Multiplex Fluorescent V2 assay Species: Fish
Gene Name: atp8a1; tpm3b; pycr3 Sample Type: FFPE Research Area: Development
Article:
Differential regulation of coronal and lambdoid suture patency by PTHLH and HHIP activity in mice
(2025) Development (Cambridge, England).
Author: Saturne, MD et al.
Motch Perrine, SM,
Li, Q,
Richtsmeier, JT,
Jabs, EW,
van Bakel, H,
Holmes, G,
 Publication Date: Fri, 09/26/2025 - 00:00 PMID: 41000054
Product Code: 323100 Assay: RNAscope Multiplex Fluorescent V2 assay Species: Mouse
Gene Name: Gli1; Hhip; Ihh; Ptch1; Pth1r; Pthlh; Sp7 Sample Type: Fixed Frozen,Fresh Frozen Research Area: Development
Article:
Dynamics of YAP localization and transcript activity in human oocytes and granulosa cells across early-stage folliculogenesis: an exploratory investigation
(2025) Journal of assisted reproduction and genetics.
Author: Machlin, JH et al.
Potocsky, K,
Kruger, RE,
Spence, J,
Padmanabhan, V,
Shikanov, A,
 Publication Date: Fri, 09/26/2025 - 00:00 PMID: 40999292
Product Code: 323100 Assay: RNAscope Multiplex Fluorescent V2 assay Species: Human
Gene Name: CTGF Sample Type: Research Area: Reproduction
Article:
Human macula formation involves two waves of retinoic acid suppression via CYP26A1 that modulate cell cycle exit and cone subtype specification
(2025) Stem cell reports:102647.
Author: Harding, P et al.
Wojtynska, M,
Smith, AJ,
Ali, RR,
Pearson, RA,
 Publication Date: Thu, 09/25/2025 - 00:00 PMID: 41005311
Product Code: 323100 Assay: RNAscope Multiplex Fluorescent V2 assay Species: Human
Gene Name: CYP26A1; FGF8 Sample Type: Fixed Frozen Research Area: Stem Cell
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