THPTA

Name: THPTA
Brand: Tocris Bioscience
SKU: 7863

Tocris Bioscience, part of Bio-Techne | Catalog # 7863

COA / SDS

Click chemistry auxiliary reagent; accelerating ligand for copper-catalyzed azide-alkyne cycloaddition reaction

Key Product Details

Description:	Click chemistry auxiliary reagent; accelerating ligand for copper-catalyzed azide-alkyne cycloaddition reaction
Chemical Name:	Tris[(1-(3-hydroxypropyl)-1H-1,2,3-triazol-4-yl]methyl)amine
Purity:	≥95% (HPLC)
Molecular Weight:	434.51

View Full Technical Details for THPTA

Technical Data
Citations

Biological Activity for THPTA

THPTA is a click chemistry auxiliary reagent. It is a stabilizing ligand for copper-catalyzed azide-alkyne cycloaddition reactions.

Technical Data for THPTA

M. Wt	434.51
Formula	C₁₈H₃₀N₁₀O₃
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	760952-88-3
PubChem ID	85325313
InChi Key	VAKXPQHQQNOUEZ-UHFFFAOYSA-N
Smiles	OCCCN1N=NC(CN(CC2=CN(CCCO)N=N2)CC3=CN(CCCO)N=N3)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for THPTA

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	water	43.45	100
	DMSO	43.45	100

Preparing Stock Solutions for THPTA

The following data is based on the product molecular weight 434.51.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.30 mL	11.51 mL	23.01 mL
5 mM	0.46 mL	2.30 mL	4.60 mL
10 mM	0.23 mL	1.15 mL	2.30 mL
50 mM	0.05 mL	0.23 mL	0.46 mL

Molarity Calculator

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Reconstitution Calculator

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References for THPTA

References are publications that support the biological activity of the product.

Fantoni A Hitchhiker's guide to click-chemistry with nucleic acids. Chem.Rev. 2021 PMID: 33443411
Zhu Biomimetic α-selective ribosylation enables two-step modular synthesis of biologically important ADP-ribosylated peptides. Nat.Commun. 2020 PMID: 33154359