TBTA

Name: TBTA
Brand: Tocris Bioscience
SKU: 7862

Tocris Bioscience, part of Bio-Techne | Catalog # 7862

COA / SDS

Click chemistry auxiliary reagent; stabilizing ligand for copper-catalyzed azide-alkyne cycloaddition reaction

Key Product Details

Description:	Click chemistry auxiliary reagent; stabilizing ligand for copper-catalyzed azide-alkyne cycloaddition reaction
Chemical Name:	Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine
Purity:	≥97% (HPLC)
Molecular Weight:	530.6

View Full Technical Details for TBTA

Technical Data
Citations

Biological Activity for TBTA

TBTA is a click chemistry auxiliary reagent. It is a stabilizing ligand for copper-catalyzed azide-alkyne cycloaddition reactions.

Technical Data for TBTA

M. Wt	530.6
Formula	C₃₀H₃₀N₁₀
Storage	Store at -20°C
Purity	≥97% (HPLC)
CAS Number	510758-28-8
PubChem ID	11203363
InChi Key	WKGZJBVXZWCZQC-UHFFFAOYSA-N
Smiles	N1(CC2=CC=CC=C2)N=NC(CN(CC3=CN(CC4=CC=CC=C4)N=N3)CC5=CN(CC6=CC=CC=C6)N=N5)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for TBTA

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	53.06	100

Preparing Stock Solutions for TBTA

The following data is based on the product molecular weight 530.6.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.88 mL	9.42 mL	18.85 mL
5 mM	0.38 mL	1.88 mL	3.77 mL
10 mM	0.19 mL	0.94 mL	1.88 mL
50 mM	0.04 mL	0.19 mL	0.38 mL

Molarity Calculator

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Reconstitution Calculator

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References for TBTA

References are publications that support the biological activity of the product.

Fantoni A hitchhiker's guide to click-chemistry with nucleic acids. Chem.Rev. 2021 PMID: 33443411
Kour Stapling proteins in the RELA complex inhibits TNFα-induced nuclear translocation of RELA. RSC Chem.Biol. 2021 PMID: 35128406
Pang In situ identification of cellular drug targets in mammalian tissue. Cell 2022 PMID: 35483372