EGTA
Tocris Bioscience, part of Bio-Techne | Catalog # 2807
Calcium chelating agent
Key Product Details
Description
Calcium chelating agent
Product Description
EGTA is a calcium chelator; protects against cell death caused by nitric oxide-induced calcium influx into nerve cells.Product Specifications
Molecular Weight
380.35
Formula
C14H24N2O10
Storage
Store at RT
Chemical Name
Ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetraacetic acid
CAS Number
67-42-5
PubChem ID
6207
InChI Key
DEFVIWRASFVYLL-UHFFFAOYSA-N
SMILES
O=C(CN(CC(O)=O)CCOCCOCCN(CC(O)=O)CC(O)=O)O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| 1M NaOH | 38.03 | 100 |
Preparing Stock Solutions
for EGTA
The following data is based on the product molecular weight 380.35
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.63 mL | 13.15 mL | 26.29 mL |
| 5 mM | 0.53 mL | 2.63 mL | 5.26 mL |
| 10 mM | 0.26 mL | 1.31 mL | 2.63 mL |
| 50 mM | 0.05 mL | 0.26 mL | 0.53 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Fisher Catalytic superoxide scavenging by metal complexes of the calcium chelator EGTA and contrast agent EHPG. Biochem.Biophy.Res.Comms.
- Boullerne Role of calcium in nitric oxide-induced cytotoxicity: EGTA protects mouse oligodendrocytes. J.Neurosci.Res. 2001 PMID: 11169622
Product Specific Notices for EGTA
For research use only
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