DBCO-NHS

Name: DBCO-NHS
Brand: Tocris Bioscience
SKU: 7921

Tocris Bioscience, part of Bio-Techne | Catalog # 7921

Citations (1)

COA / SDS

Amine reactive and azide reactive building block

Key Product Details

Description:	Amine reactive and azide reactive building block
Chemical Name:	2,5-Dioxo-1-pyrrolidinyl-11,12-didehydro-γ-oxodibenz[b,f]azocine-5(6H)-butanoate
Purity:	≥95% (HPLC)
Molecular Weight:	402.4

View Full Technical Details for DBCO-NHS

Technical Data
Citations

Biological Activity for DBCO-NHS

DBCO-NHS is an amine reactive and azide reactive building block. It can be used for copper-free click cycloaddition reactions.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data for DBCO-NHS

M. Wt	402.4
Formula	C₂₃H₁₈N₂O₅
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	1353016-71-3
PubChem ID	77078178
InChi Key	XCEBOJWFQSQZKR-UHFFFAOYSA-N
Smiles	O=C(ON1C(=O)CCC1=O)CCC(=O)N2C=3C=CC=CC3C#CC=4C=CC=CC4C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for DBCO-NHS

References are publications that support the biological activity of the product.

Ge Chemoselective bioconjugation of amyloidogenic protein antigens to PEGylated microspheres enables detection of α-Synuclein autoantibodies in human plasma. Bioconjug.Chem. 2022 PMID: 35020392
Liu Strain-promoted "click" modification of a mesoporous metal-organic framework. J.Am.Chem.Soc. 2012 PMID: 23113571