Zinterol hydrochloride is a potent and selective β₂-adrenoceptor agonist (pK_B values are 8.3 and < 5.7 for β₂ and β₁ receptors respectively, as measured in human artery).

Product Specifications

Molecular Weight

414.95

Formula

C₁₉H₂₆N₂O₄S.HCl

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

N-[5-[2-[(1,1-Dimethyl-2-phenylethyl)amino]-1-hydroxyethyl]-2-hydroxyphenyl]methanesulphonamide hydrochloride

CAS Number

38241-28-0

PubChem ID

37989

InChI Key

LVNUBJDWJFOMKH-UHFFFAOYSA-N

SMILES

OC1=C(NS(=O)(C)=O)C=C(C(O)CNC(C)(C)CC2=CC=CC=C2)C=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	water	2.07	5
	DMSO	41.49	100

Preparing Stock Solutions for Zinterol hydrochloride

The following data is based on the product molecular weight 414.95

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.41 mL	12.05 mL	24.10 mL
5 mM	0.48 mL	2.41 mL	4.82 mL
10 mM	0.24 mL	1.20 mL	2.41 mL
50 mM	0.05 mL	0.24 mL	0.48 mL

Calculators

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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Background References

References are publications that support the biological activity of the product.

Hutchinson Agonist effects of zinterol at the mouse and human β3-adrenoceptor. Naunyn Schmiedebergs Arch.Pharmacol. 2006 PMID: 16601951
Kauman Four β-adrenoceptor subtypes in the mammalian heart. TiPS 1997 PMID: 9133774
Arvydas Skeberdis Beta-2 adrenergic activation of L-type Ca²⁺ current in cardiac myocytes. J.Pharmacol.Exp.Ther. 1997 PMID: 9353357

Zinterol hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 1051

Key Product Details

Description

Alternative Names

View all Adrenergic beta-2 Receptor Agonists »

Product Description