Z-VRPR-FMK trifluoroacetate salt
Tocris Bioscience, part of Bio-Techne | Catalog # 4645
Irreversible MALT1 inhibitor
Discontinued Product
4645 has been discontinued.
View all MALT1 products.
Product Description
Z-VRPR-FMK trifluoroacetate salt is an irreversible MALT1 inhibitor. Suppresses T cell activation-induced cleavage of Bcl-10 in a dose-dependent manor. Reduces Jurkat cell adhesion to fibronectin. Cell permeable.This peptide is supplied in gross weight.
Licensing Information
Sold under licence from UNIL under the licenced patentsImportant Information
This product is sold as a TFA salt. The stoichiometry of the salt and hydration levels vary from batch to batch. This product is sold in gross weight with the batch specific Net Product Content (free base) available on the Certificate of Analysis.Product Specifications
Formula
C31H49FN10O6.xCF3CO2H
Storage
Store at -20°C
Purity
≥95% (HPLC)
PubChem ID
121513848
InChI Key
WIPHXOQUHDJLCU-WTJMUODPSA-N
SMILES
OC(=O)C(F)(F)F.CC(C)[C@H](NC(=O)OCC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)NC(CCCNC(N)=N)C(=O)CF
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water with gentle warming and with sonication |
Calculators
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Rebeaud The proteolytic activity of the paracaspase MALT1 is key in T cell activation. Nat.Immunol. 2008 PMID: 18264101
Product Specific Notices for Z-VRPR-FMK trifluoroacetate salt
For research use only
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