Y-29794 oxalate

Name: Y-29794 oxalate
Brand: Tocris Bioscience
SKU: 1634

Tocris Bioscience, part of Bio-Techne | Catalog # 1634

COA / SDS

Prolyl endopeptidase inhibitor

Discontinued Product

1634 has been discontinued. View all Additional Synthetic Protease Inhibitors products.

Key Product Details

Description:	Prolyl endopeptidase inhibitor
Chemical Name:	[2-[[8-(Dimethylamino)octyl]thio]-6-(1-methylethyl)-3-pyridinyl]-2-thienylmethanone oxalate
Purity:	≥96% (HPLC)
Molecular Weight:	508.69

View Full Technical Details for Y-29794 oxalate

Technical Data
Citations

Biological Activity for Y-29794 oxalate

Y-29794 oxalate is a inhibitor of prolyl endopeptidase, a serine peptidase that may be implicated in the biosynthesis of amyloid β-peptide. Potently inhibits rat brain prolyl endopeptidase (K_i = 0.95 nM) in vitro, and prevents amyloid β-peptide deposition in vivo. Orally active and brain penetrant.

Technical Data for Y-29794 oxalate

M. Wt	508.69
Formula	C₂₃H₃₄N₂OS₂.C₂H₂O₄
Storage	Store at -20°C
Purity	≥96% (HPLC)
CAS Number	146794-84-5
PubChem ID	45073463
InChi Key	UUSSHPPSOUAHHP-UHFFFAOYSA-N
Smiles	O=C(C2=CC=CS2)C1=CC=C(C(C)C)N=C1SCCCCCCCCN(C)C.O=C(C(=O)O)O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Y-29794 oxalate

References are publications that support the biological activity of the product.

Nakajima Y-29794 - a non-peptide prolyl endopeptidase inhibitor that can penetrate into the brain. Neurosci.Lett. 1992 PMID: 1436628
Kato Prevention of amyloid-like deposition by a selective prolyl endopeptidase inhibitor, Y-29794, in senescence-accelerated mouse. J.Pharmacol.Exp.Ther. 1997 PMID: 9336340

Y-29794 oxalate

Tocris Bioscience, part of Bio-Techne | Catalog # 1634

Key Product Details

Biological Activity for Y-29794 oxalate

Technical Data for Y-29794 oxalate

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Y-29794 oxalate

Product Documents for Y-29794 oxalate

COA

Certificate of Analysis

SDS

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