VUF 11222
Tocris Bioscience, part of Bio-Techne | Catalog # 5668
High affinity non-peptide CXCR3 agonist
Key Product Details
Description
High affinity non-peptide CXCR3 agonist
Product Description
VUF 11222 is a high affinity non-peptide CXCR3 agonist (pKi = 7.2).Product Specifications
Molecular Weight
552.33
Formula
C25H31BrIN
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
2'-Bromo-N-[[(1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]methyl]-N,N-dimethyl-[1,1'-biphenyl]-4-methanaminium iodide
CAS Number
1414376-84-3
PubChem ID
71459294
InChI Key
IXXWHYDKYNWDKJ-IUQUCOCYSA-M
SMILES
C[N+](CC1=CC=C(C2=CC=CC=C2Br)C=C1)(C)CC3=CC[C@H]4C[C@@H]3C(C)4C.[I-]
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 55.23 | 100 | |
| Ethanol | 5.52 | 10 with gentle warming |
Preparing Stock Solutions
for VUF 11222
The following data is based on the product molecular weight 552.33
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.81 mL | 9.05 mL | 18.11 mL |
| 5 mM | 0.36 mL | 1.81 mL | 3.62 mL |
| 10 mM | 0.18 mL | 0.91 mL | 1.81 mL |
| 50 mM | 0.04 mL | 0.18 mL | 0.36 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Wijtmans Chemical subtleties in small-molecule modulation of peptide receptor function: the case of CXCR3 biaryl-type ligands. J.Med.Chem. 2012 PMID: 23150943
Product Specific Notices for VUF 11222
For research use only
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