VU 0357121

Name: VU 0357121
Brand: Tocris Bioscience
SKU: 4437

Tocris Bioscience, part of Bio-Techne | Catalog # 4437

COA / SDS

Positive allosteric modulator of mGlu5 receptors

Discontinued Product

4437 has been discontinued. View all Group I mGluR Modulators products.

Key Product Details

Description:	Positive allosteric modulator of mGlu₅ receptors
Chemical Name:	4-Butoxy-N-(2,4-difluorophenyl)benzamide
Purity:	≥99% (HPLC)
Molecular Weight:	305.32

View Full Technical Details for VU 0357121

Technical Data
Citations

Biological Activity for VU 0357121

VU 0357121 is a positive allosteric modulator of mGlu₅ receptors (EC₅₀ = 33 nM). Binds to a site distinct from that bound by MPEP (Cat. No. 1212).

Technical Data for VU 0357121

M. Wt	305.32
Formula	C₁₇H₁₇F₂NO₂
Storage	Store at +4°C
Purity	≥99% (HPLC)
CAS Number	433967-28-3
PubChem ID	2296132
InChi Key	AHCYOTLTLQTPSU-UHFFFAOYSA-N
Smiles	O=C(NC2=C(F)C=C(F)C=C2)C1=CC=C(OCCCC)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for VU 0357121

References are publications that support the biological activity of the product.

Hammond Discovery of a novel chemical class of mGlu₅ allosteric ligands with distinct modes of pharmacology. ACS Chem.Neurosci. 2010 PMID: 20981342

VU 0357121

Tocris Bioscience, part of Bio-Techne | Catalog # 4437

Key Product Details

Biological Activity for VU 0357121

Technical Data for VU 0357121

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for VU 0357121

Product Documents for VU 0357121

COA

Certificate of Analysis

SDS

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