VH 101 phenol-alkylC6-amine
Tocris Bioscience, part of Bio-Techne | Catalog # 7294
VHL ligand with alkyl linker and terminal amine for onward chemistry
Key Product Details
Description
VHL ligand with alkyl linker and terminal amine for onward chemistry
Product Description
VH 101 phenol-alkylC6-amine is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkylC6 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.Please contact us for SD files of our available Degrader Building Blocks.
PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Licensing Information
Sold under licence from the University of Dundee.Usage guidelines
This product is provided for use in onward chemistry. Suitable solvents can be used.Product Specifications
Molecular Weight
704.72
Formula
C32H46FN5O5S.2HCl
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
(2S,4R)-N-(2-((6-Aminohexyl)oxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride
CAS Number
2564467-16-7
InChI Key
BKJRFJDVCDFVCY-SGROTYDGSA-N
SMILES
CC1=C(SC=N1)C2=CC=C(CNC([C@@H]3C[C@@H](O)CN3C([C@@H](NC(C4(CC4)F)=O)C(C)(C)C)=O)=O)C(OCCCCCCN)=C2.Cl.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Product Specific Notices for VH 101 phenol-alkylC6-amine
For research use only
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