UoS 12258

Tocris Bioscience, part of Bio-Techne | Catalog # 6353

Positive allosteric modulator of AMPA receptors
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Key Product Details

Description

Positive allosteric modulator of AMPA receptors

View all AMPA Receptor Modulators »

Product Description

UoS 12258 is a positive allosteric modulator of AMPA receptors (pEC50 = 5.2 for potentiation of AMPA-mediated currents in vitro). Also potentiates AMPA-mediated synaptic responses in vivo. Improves performance of rats in various learning and memory paradigms

Product Specifications

Molecular Weight

334.41

Formula

C17H19FN2O2S

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide

CAS Number

875927-64-3

PubChem ID

46398805

InChI Key

QXQSUBKWSHMXDP-INIZCTEOSA-N

SMILES

CC(S(=O)(N[C@H]1CC2=CC=C(C3=CN=C(C=C3)F)C=C2C1)=O)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 33.44 100

Preparing Stock Solutions for UoS 12258

The following data is based on the product molecular weight 334.41

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.99 mL 14.95 mL 29.90 mL
5 mM 0.60 mL 2.99 mL 5.98 mL
10 mM 0.30 mL 1.50 mL 2.99 mL
50 mM 0.06 mL 0.30 mL 0.60 mL

Calculators

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Product Documents for UoS 12258

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for UoS 12258

For research use only

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