U0124

Name: U0124
Brand: Tocris Bioscience
SKU: 1868

Tocris Bioscience, part of Bio-Techne | Catalog # 1868

Citations (11)

COA / SDS

Inactive analog of U0126 (Cat. No. 1144)

Discontinued Product

1868 has been discontinued. View all MEK Inhibitors products.

Key Product Details

Description:	Inactive analog of U0126 (Cat. No. 1144)
Chemical Name:	Bis[amino(methylthio)methylene]butanedinitrile
Molecular Weight:	226.31

View Full Technical Details for U0124

Technical Data
Citations

Biological Activity for U0124

U0124 is an inactive analog of U0126 (Cat. No. 1144). Does not inhibit MEK at concentrations up to 100 μM. Used as a negative control.

Active Analog also available.

Technical Data for U0124

M. Wt	226.31
Formula	C₈H₁₀N₄S₂
Storage	Store at RT
CAS Number	108923-79-1
PubChem ID	5842955
InChi Key	LBQNBMSPTURKGS-KQQUZDAGSA-N
Smiles	N/C(SC)=C(\C(C#N)=C(SC)/N)/C#N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for U0124

References are publications that support the biological activity of the product.

Fitzgerald Regulation of voltage-dependent calcium channels in rat sensory neurones involves a Ras-mitogen-activated protein kinase pathway. J.Physiol. 2000 PMID: 10990531
Sekar Concerted transcriptional activation of the low density lipoprotein receptor gene by Ins and luteinizing hormone in cultured porcine granulosa-luteal cells: possible convergence of protein kinase A, phosphatidylinositol 3-kinase, and mitogen-activated pro Endocrinology 2001 PMID: 11416012
Favata Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J.Biol.Chem. 1998 PMID: 9660836

U0124

Tocris Bioscience, part of Bio-Techne | Catalog # 1868

Key Product Details

Biological Activity for U0124

Technical Data for U0124

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for U0124

Product Documents for U0124

COA

Certificate of Analysis

SDS

CONTACT INFORMATION

Stay Connected