Tramiprosate

Tocris Bioscience, part of Bio-Techne | Catalog # 3619

Targets soluble Aβ to decrease amyloid plaque deposition. Also GABA analog
Discontinued Product
3619 has been discontinued. View all Amyloid beta Peptides products.

Key Product Details

Description

Targets soluble Aβ to decrease amyloid plaque deposition. Also GABA analog

Alternative Names

Homotaurine

View all Amyloid beta Peptides »

Product Description

Tramiprosate is a sulfated glycosaminoglycan (sGAG) mimetic that targets soluble amyloid β (Aβ) and maintains Aβ in a non-fibrillar form. Decreases Aβ42-induced neuronal death and inhibits amyloid deposition in vitro. Decreases brain amyloid plaque load by 30%, increases tau polymerization and is brain penetrant. Also a GABA analog that protects against the convulsant and cytotoxic activity of kainic acid in vivo.

Product Specifications

Molecular Weight

139.17

Formula

C3H9NO3S

Storage

Store at +4°C

Chemical Name

3-Amino-1-propanesulfonic acid

CAS Number

3687-18-1

PubChem ID

1646

InChI Key

SNKZJIOFVMKAOJ-UHFFFAOYSA-N

SMILES

NCCCS(=O)(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 13.92 100

Preparing Stock Solutions for Tramiprosate

The following data is based on the product molecular weight 139.17

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 7.19 mL 35.93 mL 71.85 mL
5 mM 1.44 mL 7.19 mL 14.37 mL
10 mM 0.72 mL 3.59 mL 7.19 mL
50 mM 0.14 mL 0.72 mL 1.44 mL

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

x
=
x

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product.

Product Documents for Tramiprosate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Tramiprosate

For research use only

Privacy Policy
Cookie Policy
Site Map
© Copyright 2026 Bio-Techne. All Rights Reserved. All trademarks and registered trademarks are the property of Bio-Techne and its brands unless otherwise specified.