TLQP 21

Name: TLQP 21
Brand: Tocris Bioscience
SKU: 3051

Tocris Bioscience, part of Bio-Techne | Catalog # 3051

Citations (7)

COA / SDS

VGF-derived peptide

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Technical Data
Citations & Reviews

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

VGF-derived peptide

View all Additional Trk Receptor Peptides »

Product Description

TLQP 21 is a VGF-derived peptide; spans residues 556-576 of the precursor sequence. Protects cerebellar granule cells (CGCs) from serum and potassium deprivation-induced apoptosis. Increases energy expenditure and prevents early phase diet-induced diabetes.

Product Specifications

Molecular Weight

2432.77

Formula

C₁₀₇H₁₇₀N₄₀O₂₆

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

869988-94-3

PubChem ID

16158480

InChI Key

PWWMOXVVMRPYJS-IWCKOKPFSA-N

SMILES

[H]N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 1mg/ml in water

Calculators

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Background References

References are publications that support the biological activity of the product.

Bartolomucci TLQP-21, a VGF-derived peptide, increases energy expenditure and prevents the early phase of diet-induced obesity. Proc.Natl.Acad.Sci. USA
Jethwa VGF-derived peptide, TLQP-21, regulates food intake and body weight in Siberian hamsters. Endocrinol.
Severini TLQP-21, a neuroendocrine VGF-derived peptide, prevents cerebellar granule cell death induced by serum and potassium deprivation. J.Neurochem. 2008 PMID: 18173805