Tiotropium bromide

Tocris Bioscience, part of Bio-Techne | Catalog # 5902

Potent muscarinic receptor antagonist
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Key Product Details

Description

Potent muscarinic receptor antagonist

Alternative Names

Ba 679 BR

View all Non-selective mAChR Antagonists »

Product Description

Tiotropium bromide is a potent muscarinic receptor antagonist. Inhibits electrical field stimulation-induced contraction of guinea pig trachea in vitro (IC50 = 0.17 nM). Induces smooth muscle relaxation and bronchodilation.

Product Specifications

Molecular Weight

472.42

Formula

C19H22BrNO4S2

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

(1α,2β,4β,5α,7β)-7-[(2-Hydroxy-2,2-di-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane bromide

CAS Number

136310-93-5

PubChem ID

5487426

InChI Key

DQHNAVOVODVIMG-RGECMCKFSA-M

SMILES

C[N+]1(C)[C@]2([H])[C@H]3[C@H](O3)[C@@]1([H])C[C@@H](OC(C(C4=CC=CS4)(O)C5=CC=CS5)=O)C2.[Br-]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 9.45 20
DMSO 47.24 100

Preparing Stock Solutions for Tiotropium bromide

The following data is based on the product molecular weight 472.42

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.12 mL 10.58 mL 21.17 mL
5 mM 0.42 mL 2.12 mL 4.23 mL
10 mM 0.21 mL 1.06 mL 2.12 mL
50 mM 0.04 mL 0.21 mL 0.42 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Tiotropium bromide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Tiotropium bromide

For research use only

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