Thalidomide 4'-oxyacetamide-alkylC4-amine

Tocris Bioscience, part of Bio-Techne | Catalog # 6469

Cereblon ligand with alkyl linker and terminal amine for onward chemistry
Discontinued Product
6469 has been discontinued. View all Degrader Building Blocks products.

Key Product Details

Description

Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Alternative Names

Thalidomide - linker 3

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Product Description

Thalidomide 4'-oxyacetamide-alkylC4-amine is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a short alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

This product has been recently renamed. The previous name for this product was Thalidomide - linker 3

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Product Specifications

Molecular Weight

438.86

Formula

C19H22N4O6.HCl

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

N-(4-Aminobutyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide hydrochloride

CAS Number

2245697-86-1

PubChem ID

134160248

InChI Key

UZDTXDUTMCCMDO-UHFFFAOYSA-N

SMILES

NCCCCNC(COC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O)=O.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Background References

References are publications that support the biological activity of the product.

Product Documents for Thalidomide 4'-oxyacetamide-alkylC4-amine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Thalidomide 4'-oxyacetamide-alkylC4-amine

For research use only

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