TFLLR-NH2
Tocris Bioscience, part of Bio-Techne | Catalog # 1464
PAR1-activating peptide
Key Product Details
Description
PAR1-activating peptide
Product Description
TFLLR-NH2 is a peptide derived from the protease-activated receptor-1 (PAR1) that acts as a PAR1 selective agonist (EC50 = 1.9 μM). Stimulates PAR1-mediated plasma extravasation in vivo.Control Peptide also available.
Product Specifications
Molecular Weight
647.82
Formula
C31H53N9O6
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
197794-83-5
PubChem ID
10146183
InChI Key
ANAMCEKSRDPIPX-GFGQVAFXSA-N
SMILES
[H]N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Hollenberg Proteinase-activated receptors: structural requirements for activity, receptor cross-reactivity, and receptor selectivity of receptor-activating peptides. Can.J.Physiol.Pharmacol. 1997 PMID: 9315351
- Kawabata Characterization of the protease-activated receptor-1-mediated contraction and relaxation in the rat duodenal smooth muscle. Life Sci. 2000 PMID: 11065174
- de Garavilla Agonists of proteinase-activated receptor 1 induce plasma extravasation by a neurogenic mechanism. Br.J.Pharmacol. 2001 PMID: 11487506
Product Specific Notices for TFLLR-NH2
For research use only
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