Tertiapin LQ
Tocris Bioscience, part of Bio-Techne | Catalog # 4339
Selective Kir1.1 blocker; derivative of tertiapin-Q (Cat. No. 1316)
Discontinued Product
4339 has been discontinued.
View all Inward Rectifier Potassium Channel Blockers products.
Key Product Details
Description
Selective Kir1.1 blocker; derivative of tertiapin-Q (Cat. No. 1316)
Product Description
Tertiapin LQ is a blocker of Kir1.1 channels; displays >250-fold selectivity for Kir1.1 (Kd values are 1.1, 274 and 361 nM for Kir1.1, Kir3.1/3.2 and Kir3.1/3.4 respectively). Derivative of tertiapin-Q (Cat. No. 1316).Product Specifications
Molecular Weight
2428.03
Formula
C106H179N33O24S4
Storage
Store at -20°C
PubChem ID
90488935
InChI Key
WUMIWMIQOSXVPZ-ZPWFPUPGSA-N
SMILES
[H]N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CSSC[C@@H]2NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]3CCCN3C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC3=CNC4=C3C=CC=C4)NC2=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)NC(=O)[C@H](CC(N)=O)NC1=O)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 2mg/ml in 20% acetonitrile / water |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Ramu Engineered specific and high-affinity inhibitor for a subtype of inward-rectifier K+ channels. Proc.Natl.Acad.Sci.USA 2008 PMID: 18669667
Product Specific Notices for Tertiapin LQ
For research use only
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