TC 1698 dihydrochloride

Name: TC 1698 dihydrochloride
Brand: Tocris Bioscience
SKU: 2518

Tocris Bioscience, part of Bio-Techne | Catalog # 2518

COA / SDS

α7-selective agonist

Discontinued Product

2518 has been discontinued. View all Nicotinic (a7) Receptor Agonists products.

Key Product Details

Description:	α7-selective agonist
Chemical Name:	2-(3-Pyridinyl)-1-azabicyclo[3.2.2]nonane dihydrochloride
Purity:	≥98% (HPLC)
Molecular Weight:	275.22

View Full Technical Details for TC 1698 dihydrochloride

Technical Data
Citations

Biological Activity for TC 1698 dihydrochloride

TC 1698 dihydrochloride is a selective nicotinic α7 receptor agonist (EC₅₀ = 440 nM). Also displays weak partial agonist/antagonist activity at β-subunit-containing receptors. Neuroprotective.

Technical Data for TC 1698 dihydrochloride

M. Wt	275.22
Formula	C₁₃H₁₈N₂.2HCl
Storage	Desiccate at RT
Purity	≥98% (HPLC)
CAS Number	787587-06-8
PubChem ID	21094258
InChi Key	ZQUQBCHNSBJMCG-UHFFFAOYSA-N
Smiles	C1(C2N3CCC(CC3)CC2)=CC=CN=C1.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for TC 1698 dihydrochloride

References are publications that support the biological activity of the product.

Papke Rhesus monkey α7 nicotinic acetylcholine receptors: comparisons to human α7 receptors expressed in Xenopus oocytes. Eur.J.Pharmacol. 2005 PMID: 16266703
Marrero The neuroprotective effect of 2-(3-Pyridyl)-1-azabicyclo[3.2.2]nonane (TC-1698), a novel α7 ligand, is prevented through angiotensin II activation of a tyrosine phosphatase. J.Pharmacol.Exp.Ther. 2004 PMID: 14722323

TC 1698 dihydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 2518

Key Product Details

Biological Activity for TC 1698 dihydrochloride

Technical Data for TC 1698 dihydrochloride

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for TC 1698 dihydrochloride

Product Documents for TC 1698 dihydrochloride

COA

Certificate of Analysis

SDS

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