T 0070907

Tocris Bioscience, part of Bio-Techne | Catalog # 2301

Highly potent and selective covalent PPARγ antagonist
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Key Product Details

Description

Highly potent and selective covalent PPARγ antagonist

View all PPAR gamma Receptor Antagonists »

Product Description

T 0070907 is a potent and selective irreversible PPARγ antagonist (IC50 = 1 nM). Displays > 800-fold selectivity for PPARγ over PPARα and PPARδ. Blocks transcriptional activity of PPARγ in vitro and inhibits Rosiglitazone-induced adipogenesis.

Product Specifications

Molecular Weight

277.67

Formula

C12H8N3O3Cl

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

2-Chloro-5-nitro-N-4-pyridinylbenzamide

CAS Number

313516-66-4

PubChem ID

2777391

InChI Key

FRPJSHKMZHWJBE-UHFFFAOYSA-N

SMILES

[O-][N+](=O)C1=CC=C(Cl)C(=C1)C(=O)NC1=CC=NC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
1eq. HCl 27.77 100
DMSO 27.8 100

Preparing Stock Solutions for T 0070907

The following data is based on the product molecular weight 277.67

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.60 mL 18.01 mL 36.01 mL
5 mM 0.72 mL 3.60 mL 7.20 mL
10 mM 0.36 mL 1.80 mL 3.60 mL
50 mM 0.07 mL 0.36 mL 0.72 mL

Calculators

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Product Documents for T 0070907

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for T 0070907

For research use only

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