Sulindac

Tocris Bioscience, part of Bio-Techne | Catalog # 1707

Cyclooxygenase inhibitor (following metabolism to sulindac sulfide)
Discontinued Product
1707 has been discontinued. View all Cyclooxygenase Inhibitors products.

Key Product Details

Description

Cyclooxygenase inhibitor (following metabolism to sulindac sulfide)

View all Cyclooxygenase Inhibitors »

Product Description

Prodrug. Metabolizes to sulindac sulfide, a cyclooxgenase inhibitor that represses ras signaling, and sulindac sulfone, an antitumor agent, following oral administration in vivo. Widely used anti-inflammatory agent.

Product Specifications

Molecular Weight

356.41

Formula

C20H17FO3S

Storage

Store at RT

Purity

≥99% (HPLC)

Chemical Name

(1Z)-5-Fluoro-2-methyl-1-[[4-(methylsulfinyl)phenyl]methylene]-1H-indene-3-acetic acid

CAS Number

38194-50-2

PubChem ID

1548887

InChI Key

MLKXDPUZXIRXEP-MFOYZWKCSA-N

SMILES

FC1=CC=C(/C(C(C)=C3CC(O)=O)=C\C2=CC=C(S(C)=O)C=C2)C3=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 35.64 100
Ethanol 8.91 25

Preparing Stock Solutions for Sulindac

The following data is based on the product molecular weight 356.41

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.81 mL 14.03 mL 28.06 mL
5 mM 0.56 mL 2.81 mL 5.61 mL
10 mM 0.28 mL 1.40 mL 2.81 mL
50 mM 0.06 mL 0.28 mL 0.56 mL

Calculators

Molarity Calculator

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Dilution Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Sulindac

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Sulindac

For research use only

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