SSM 3 trifluoroacetate
Tocris Bioscience, part of Bio-Techne | Catalog # 5253
Potent furin inhibitor
Product Description
SSM 3 trifluoroacetate is a potent furin inhibitor (EC50 = 54 nM). Blocks furin-dependent cell surface processing of anthrax protective antigen-83 in vitro.Product Specifications
Molecular Weight
952.66
Formula
C22H32N12O2.4CF3CO2H
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
rel-N,N''-[[(1R,3S,4S,6R)-4,6-Bis[(aminoiminomethyl)amino]-1,3-cyclohexanedyil]bis(oxy-4,1-phenylene)]bisguanidine tetratrifluoroacetate salt
CAS Number
2320930-10-5
PubChem ID
121513857
InChI Key
JYRRXGHBFAELIV-YAOLEPIASA-N
SMILES
NC(N[C@H]1C[C@@H](NC(N)=N)[C@H](OC3=CC=C(NC(N)=N)C=C3)C[C@@H]1OC2=CC=C(NC(N)=N)C=C2)=N.FC(F)(F)C(O)=O.FC(F)(F)C(O)=O.FC(F)(F)C(O)=O.FC(F)(F)C(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 49.66 | 100 | |
| DMSO | 49.66 | 100 |
Preparing Stock Solutions
for SSM 3 trifluoroacetate
The following data is based on the product molecular weight 952.66
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.05 mL | 5.25 mL | 10.50 mL |
| 5 mM | 0.21 mL | 1.05 mL | 2.10 mL |
| 10 mM | 0.10 mL | 0.52 mL | 1.05 mL |
| 50 mM | 0.02 mL | 0.10 mL | 0.21 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Remacle Selective and potent furin inhibitors protect cells from anthrax without significant toxicity. Int.J.Biochem.Cell Biol. 2010 PMID: 20197107
Product Specific Notices for SSM 3 trifluoroacetate
For research use only
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